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Objective To study the oral glucose-insulin release test (OGIRT) of insulin (Ins) secretion characteristics curve, the initial clinical evaluation applicable to individual insulin sensitivity and β cell secretory function. Methods From 12 cases of normal glucose tolerance and intravenous line OGIRT oral glucose tolerance test (IVGTT), observed OGIRT, IVGTT plasma secretion Ins frequency distribution of peak time

IDDM patients with diabetic fasting plasma insulin levels were significantly lower than its base value generally 5mu / L below OGTT insulin release after stimulation can not be increased with the increase of blood glucose. Low常呈non-peak curve, and even some patients can not be measured. NIDDM patients with diabetes and normal fasting insulin level, or slightly below normal, but to the owner of the high -

Objective: Impaired glucose area under the curve (SBG), the release of insulin area under the curve (SIns), Su-sensitive insulin sensitivity index, the commonly used clinical indicators of diabetes on non-insulin-dependent diabetes mellitus (noninsulin-dependent diabetes melitus, NIDDM) model of insulin resistance evaluation. Methods: Rats never shot the main chain of low-dose streptozotocin urine, so that